A comparative study of two preoperative thoracoscopic localization methods for solitary pulmonary nodule

CHAI Jie; LU Dong; LYU Weifu; WEI Ning; CHU Senlin; XU Beibei; WANG Lijun; YU Huafeng

Abstract：Objective To compare the clinical value of CT-guided micros coil localization and medical glue combined with methylene blue(MGMB)localization in the preoperative localization of isolated pulmonary nodules(SPN)VATS,and to ana-lyze the risk factors for complications after localization.Methods We collected 292 patients with isolated pulmonary nodules admitted to our thoracic surgery department,with 129 in the microscoil group and 163 in the MGMB group,and compared the safety and success rate of the two localization techniques,as well as their potential clinical value.Results All patients were lo-calized within 36 h before VATS,and the MGMB group had shorter localization time(7.42±2.58 vs 14.80±3.60 min,P<0.001),shorter hospital stay(5.67±2.16 vs 10.26±3.69 d,P<0.001),and shorter operative time(94.64±46.41 vs 129.64±64.70 min,P<0.001)compared with the microscoil group.The preoperative localization success rates were 96.9%(125/129)and 100%(163/163)in the two groups,respectively.No death or serious complications occurred during localization,and the complication rates were not statistically different between the two groups(P=0.902).Logistic regression analysis showed that time to localization was a risk factor for total complications(OR=1.119,95%confidence interval,1.002～1.249,P=0.045).Con-clusion Both techniques can safely and effectively localize the SPN before VATS,but the localization time and hospital stay are shorter in the MGMB group,and the practicality and potential clinical value are higher,which is worthy of clinical promotion.