Application of noninvasive left ventricular myocardial work technology in the diagnosis of coronary heart disease with-out myocardial infarction

WANG Fang; TIAN Yongfu; NA Lisha; CHENG Hua; YANG Xue; ZHOU Li

Abstract：Objective To evaluate the application value of left ventricular myocardial work(LVMW)technology in the diag-nosis of coronary heart disease without myocardial infarction.Methods 109 non-myocardial infarction patients with suspected history of ischemic chest pain attack were collected in the cardiovascular department of our hospital for this study.All patients un-derwent transthoracic echocardiography and LVMW analysis,with complete coronary angiography(CAG)data.The subjects were divided into non coronary artery stenosis group(40 cases),single-vessel coronary artery stenosis group(40 cases),and multi-vessel coronary artery stenosis group(29 cases)according to the results of CAG.The differences of transthoracic echocar-diography parameters and LVMW parameters in each group were compared.The predictive value of LVMW parameters on coro-nary stenosis was evaluated.Results GWI,GCW and GWE in coronary artery stenosis group were lower than those in matched group,while,GWW was higher than that in matched group(all P<0.05).Compared to the matched group,the changes in GLS and PSD were not significant in the single coronary artery stenosis group,but,they had significant difference in the multiple coronary artery stenosis group.GLS,GWI,GCW and GWE in the multiple coronary artery stenosis group were lower than those in the matched group,while,PSD and GWW were higher than those in matched group(all P<0.05).GWI,GWE,GCW and GWW all had the ability to predict coronary artery stenosis in the early stage,among which GWI had the best sensitivity,the largest positive likelihood ratio and the smallest negative likelihood ratio(at least one coronary artery stenosis rate≥70%).Conclusions LVMW parameters had changed in patients with coronary heart disease without myocardial infarction.GWI could be used as a non-invasive index to predict the degree of coronary artery stenosis,thereby providing a new reference direction for echocardiography screening for non-myocardial infarction coronary heart disease.