Clinical significance of incidental thyroid uptake on 18F-FDG PET/CT imaging
ZHAN Ying
HAO Shanhu
WU Xiaodan
JIAO Tingting
ZHANG Guoxu
WANG Zhiguo
Abstract：Objective To investigate the clinical significance of incidental thyroid uptake in patients subjected to 18F-FDG PET/CT imaging.Methods Images of 2817 patients who underwent 18F-FDG PET/CT in our department for suspected various non-thyroidal lesions were selected,of whom 245(8.7%)had increased thyroid 18F-FDG uptake.Their imaging was analyzed,and standardized uptake values(SUVmax)were calculated,combined with the patients'age,gender,examination,surgery and follow-up results.Results 84(34.3%)of the 245 patients with thyroid 18F-FDG uptake increased showed diffuse uptake and 161(65.7%)showed focal uptake.All patients with diffuse uptake were diagnosed with benign disease,while 29(59.2%)of the 49 patients with focal uptake who underwent pathological diagnosis had benign lesions and 20(40.8%)had malignant lesions.The SUVmax were(8.92±6.60)and(5.57±3.48)for patients with malignant and benign lesions,with statistically significant differences(P<0.05).Conclusion In patients with incidental thyroid uptake on 18F-FDG PET/CT,diffuse uptake is usually associated with benign thyroid disease,whereas,focal uptake requires further examination and evaluation,which is more benefi-cial to improve the accuracy.
Keywords：Thyroid glandPositron emission computed tomographyFluorodeoxyglucose
Publication Date：2024-05-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 43-45,55 )