Efficacy and safety of CalliSpheres drug-carrying microsphere arterial embolization for bladder cancer complicated with bleeding
LIU Song
QIAO Yuangang
WANG Qian
QIU Zhonghua
ZHANG Weiwei
Abstract：Objective To investigate the feasibility and safety of CalliSpheres drug-loaded microsphere arterial chemoemboli-zation in the treatment of bladder cancer complicated with bleeding.Methods Eleven patients with bladder cancer and Bleed-ing who received CalliSpheres drug-carrying embolization microspheres transcatheter arterial chemoembolization from January 2019 to March 2022 were selected and evaluated by Modified solid Tumor Efficacy Evaluation Criteria(mRECIST)for 3 and 6 months.The recurrence of hematuria,changes in blood indexes,adverse reactions and complications were recorded before and after treatment.Results All the 11 cases were treated with interventional embolization with a success rate of 100%.Gross he-maturia disappeared within 48-72h after surgery.In this study,the ORR of 3 and 6 months after the first treatment was 72.73%and 63.64%,and the DCR was 90.91%and 81.82%,respectively.At 9-month follow-up,all 11 patients survived.Postoperative complications included bladder pain in 8 cases,nausea and vomiting in 6 cases and fever in 2 cases,all of whom were relieved after symptomatic management.There were no ectopic embolism and other serious complications.Conclusion CalliSpheres drug-loaded microsphere arterial embolization is effective and safe in the treatment of bladder cancer complicated with bleeding.
Keywords：Bladder cancerArterial embolization chemotherapyDrug loaded microsphereBlood in the urineInterven-tionalRadiology
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 77-80 )