Efficacy of Mono-DBT combined with FFDM in the diagnosis of breast cancer

PAN Ting; DENG Xueying; FAN Linyin; ZHANG Shihan; LI Yayi; SHAO Guoliang

Abstract：Objective To investigate the detection rate and diagnostic efficacy of digital breast tomography(DBT)in the mo-nomeric position(Craniocaudal,CC or medial oblique Mediterranean Oblique,MLO)and full-field digital mammography(FFDM).Methods 141 breast cancer patients underwent breast DBT and FFDM examinations at the same time were included in this work.Two breast imaging diagnostic physicians performed monomeric and two-position readings of the patient's DBT im-ages and combined with FFDM.The pathological results were used as the gold standard for control.The detection rate and diag-nostic efficacy of monomer and bi-body DBT combined with FFDM on benign and malignant lesions of the breast were analyzed.Results 141 patients were selected according to the ACR's version of 2013 the BI-RADS system classification standard,there were 3 cases of Class A,40 cases of Class B,84 cases of Class C,and 14 cases of Class D.According to the BI-RADS rating crite-ria,the two diagnosticians used four diagnostic modalities(DBT-CC,DBT-MLO and DBT(CC + MLO)combined with FFDM and FFDM alone for the diagniosis,respectively).Conclusion The false positive rate and false negative rate of the results in both monomer and bibody positions were lower than FFDM,the accuracy,specificity and sensitivity of diagnosis were higher than FFDM,the diagnostic efficacy of FFDM + DBT bibody position was higher than that of high/low-aged diagnosticians FFDM + DBT,the accuracy,sensitivity and specificity MLO between FFDM + DBT-CC,and FFDM + DBT-MLO were higher than CC position.