Discriminatory value of APT imaging and 3D-ASL imaging in meningioma staging
ZHANG Jinhuan
CHEN Ling
LI Shuanghong
QIN Jianli
JIANG Yu
PENG Peng
LI Tao
Abstract：Objective To study the differential value of amide proton transfer(APT)imaging and three-dimensional arterial spin labeling(3D-ASL)in preoperative staging of meningiomas.Methods Twenty-five patients with pathologically con-firmed meningiomas underwent preoperative 3D-ASL,APT and conventional magnetic resonance examinations to analyze the conventional magnetic resonance manifestations of different staging meningiomas.Then,we calculated and compared the tumor regional blood flow(TBF),relative cerebral blood flow(rCBF),tumor regional APT values,contralateral CBF contralateral val-ues,and APT contralateral values of meningiomas at the corresponding locations between groups.Results The TBF and rCBF values of fibrous meningioma were lower than those of endothelial meningioma and transitional meningioma,and the differences were statistically significant(P=0.009 and 0.013<0.05);the differences between endothelial meningioma and transitional menin-gioma were not significant.The difference between APT values of fibrous meningioma and endothelial meningioma was statisti-cally significant(P=0.040<0.05).Transitional and endothelial meningiomas had their own characteristics of MRI flat scan sig-nal.Conclusion APT imaging and 3D-ASL imaging are useful for preoperative identification of fibrous,endothelial,and tran-sitional meningiomas.
Keywords：Amide proton transfer imaging3D arterial spin labelingMeningiomaPathological stagingMagnetic reso-nance imaging
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1-4 )