Diagnostic value of intravoxel incoherent motion and diffusion weighted imaging in signet ring cell carcinoma of stom-ach
YUAN Letian
SHEN Zijian
YUAN Yuchun
Abstract：Objective To investigate the differential diagnostic value of distinguishing signet ring cell carcinoma(SRCC)from non signet ring cell carcinoma(NSRCC)by intravoxel incoherent motion(IVIM)and diffusion weighted imaging(DWI).Methods 70 patients with gastric adenocarcinoma were selected from Shandong Provincial Hospital.The patients underwent preoperative DWI and IVIM scans to measure IVIM and DWI parameters,including apparent diffusion coefficient(ADC),true diffusion coefficient(D),perfusion fraction(f),and pseudo diffusion coefficient(D*).According to histological type,they were divided into signet ring cell carcinoma(25 cases)and non signet ring cell carcinoma(45 cases).The differences were compared by independent sample t-tes tand the diagnostic efficiency of distinguishing SRCC from NSRCC was analyzed by ROC curves.Results ADC and D of SRCC were significantly higher than those of NSRCC(P<0.05),but there was no significant difference inD* and f between SRCC and NSRCC(P>0.05).With ROC curve analysis representation for ADC and D,in terms of distin-guishing SRCC from NSRCC,D and ADC values had high diagnostic efficiency;the difference of AUC between D and ADC was not statistically significant(P>0.05).Conclusion IVIM and DWI can better distinguish SRCC from NSRCC,which is of great significance for the formulation of treatment plan of SRCC.
Keywords：Intravoxelincoherentmotion imagingDiffusion weighted imagingSignet ring cell carcinomaNon signet ring cell carcinomaDifferential diagnosis
Publication Date：2024-03-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 62-65 )