Study on the correlation between hypertensive grading and cerebral microbleeds evaluated by susceptibility weighted imaging

WU Rongxing; LIAO Renyin; ZHOU Weiguo; ZHOU Zhiming; WEI Sudong; FENG Jingqiang

Abstract：Objective To explore the correlation between hypertensive grading and cerebral microbleeds evaluated by sus-ceptibility weighted imaging.Methods 300 patients with hypertension who received clinical diagnosis and treatment in our hos-pital were selected and divided into grade 1 hypertension group,grade 2 hypertension group,and grade 3 hypertension group ac-cording to blood pressure levels.All patients underwent MR brain SWI examination.The number of cerebral microbleeds(CMBs)detected in the three groups were compared,and the correlation between the number of CMBs detected and the classifica-tion of hypertension was analyzed.The sensitivity,specificity,positive predictive value,and negative predictive value of SWI di-agnosis of CMBs in patients with different grades of hypertension were calculated by MedCalc.According to the results of CMBs ex-amination,CMBs were classified,and the correlation between hypertension classification and CMBs classification was analyzed.Results The positive rate of CMBs and the number of CMBs in grade 3 hypertension group were higher than those in grade 1 hy-pertension group and grade 2 hypertension group(P<0.05).The grade of hypertension was positively correlated with the number of CMBs(r>0,P<0.05).There was no significant difference in sensitivity,specificity,positive predictive value and negative predic-tive value of SWI in the diagnosis of CMBs in patients with different hypertension grades(P>0.05).The positive rates of type Ⅰ CMBs,type Ⅱ CMBs and type Ⅴ CMBs in grade 3 hypertension group were higher than those in grade 1 hypertension group and grade 2 hypertension group(P<0.05).Spearman correlation test showed that there was no significant correlation between hyper-tension classification and CMBs classification(P>0.05).Conclusion CMBs are closely related to the condition of hypertension.SWI has important application value in evaluating the distribution of CMBs in patients with different grades of hypertension.