Diagnostic value of mammography and ultrasound in different pathological types and molecular types of breast cancer in young women

GAO Wenyi; SUN Yue; NUERYEMU·Mai maiti; YAO Juan

Abstract：Objective To analyze the diagnostic value of mammography and ultrasound in young women with different patho-logical types and molecular types of breast cancer.Methods Eighty-seven cases of young women with breast cancer confirmed by pathology in our hospital were retrospectively analyzed.The basic features,pathological types,molecular typing and image features were analyzed,and the sensitivity and combined diagnostic rate of X-ray and ultrasonography were compared.Results Invasive ductal carcinoma(IDC)was the most common pathological type(46.0%),and the most common molecular subtype was Luminal B(48.3%).On mammography,IDC often appeared as an irregular mass with blurred edges.IDC and ductal carcinoma in situ(DCIS)were mainly amorphous,clustered or clustered calcification.DCIS showed calcification or other signs(structural distortion or focal asymmetry),and calcification showed segmental or diffuse distribution.Other types of cancer mainly presented as irregular or massive masses with well-defined edges.Luminal B type was mainly calcified(35.7%).Luminal A type and triple negative type were mainly mass(34.5%and 42.9%,respectively).Calcification was common in HER-2 overexpression(55.6%).There was no significant difference in aspect ratio and blood flow in and around breast lesions among different patho-logical types and molecular subtypes(all P>0.05).The sensitivity of mammography,ultrasound,and the combination of the both was 59.8%,72.4%and 82.8%,respectively.Conclusions Individual radiographic features of breast cancer in young women can be used to predict certain pathologic types of tumor.The sensitivity of ultrasonography is higher than that of mammography.Ultrasonography combined with mammography can improve the sensitivity.