The clinical value of magnetic resonance DWI combined with dynamic contrast-enhanced imaging in evaluating the dif-ferentiation degree and neurovascular invasion of rectal cancer

LI Ping; HONG Zhonghua; CAI Ruyun; ZHANG Xiaohua; GAO Yiping

Abstract：Objective To explore the value of MR diffusion-weighted imaging(DWI)combined with dynamic contrast-enhanced scanning(DCE-MRI)in the differentiation degree and neurovascular invasion of rectal cancer.Methods 85 patients with rectal cancer were selected.According to histopathological diagnosis,33 patients with nerve and vascular invasion were re-garded as the observation group,and 52 patients without nerve and vascular invasion were taken as the control group.All patients received routine MR sequence and DWI combined with DCE scanning.The ADC,eADC,PEI,TTP,MTE,SER and MSI values of the two groups and the tumors with different differentiation degrees were compared.The diagnostic efficacy of tumor ADC value,eADC value,PEI value and their combination for neurovascular invasion of rectal cancer were compared.Results The ADC value of tumor in the observation group was significantly lower than that in the control group,and the eADC value and PEI value were significantly higher than those in the control group(P<0.05).The ADC value of the poorly differentiated group was significantly lower than that of the moderately and well differentiated groups,and the eADC value and PEI value were signifi-cantly higher than those of the moderately and well differentiated groups(P<0.05).In the comparison of the diagnostic efficacy of tumor ADC value,eADC value,PEI value,and the combination of the three for neurovascular invasion of rectal cancer,the sensitivity and accuracy of the combined detection were higher than those of the three alone,and the specificity was higher than that of the eADC value and PEI value alone,with statistical significance(P<0.05).Conclusion The combination of DWI and DCE-MRI can effectively evaluate the degree of differentiation and neurovascular invasion of rectal cancer patients,and has high clinical value.