Ultrasonographic multimodal features with different molecular subtypes of breast cancer in young women

KAN Guangjuan; FU Xiaofeng; YANG Jing; HUANG Anqian; BAO Lingyun; TAN Yanjuan

Abstract：Objective To analyze the ultrasound multimodal characteristics of different molecular subtypes of breast cancer in young women.Methods We retrospectively analyzed 211 young women with breast cancer confirmed by pathology.Molecular types were classified by immunohistochemical results.We applied conventional ultrasound,three-dimensional(ABVS),color Doppler blood flow imaging and elasticity techniques,analyzed and summarized different molecular types of ultrasound signs of breast cancer in young women.Results The analysis showed that there was no significant difference in the mean age between different molecular types(F=1.337,P=0.263).Also,there was no statistical difference between the different molecular types of breast cancer in the tumor and non-mass type,shape,growth pattern,edge characteristics,coronal characteristics,posterior echo,color blood flow,resistance index,and the presence or absence of axillary lymph node metastasis(P>0.05).However,the differ-ences in the presence or absence of calcification and elasticity scores in the lesions were statistically significant(P<0.05);the differences between the different molecular types of breast cancer in different pathological types were statistically significant(x2 = 14.549,P=0.002).Conclusion Different molecular types of breast cancer in young women have different ultrasound signs.Its molecular classification can provide certain help,which is conducive to the treatment and prognosis evaluation of breast cancer in young women.