Diagnostic value of flow reserve fraction based on coronary angiography in diagnosis and treatment of coronary artery disease
JU Bin
SUN Min
LUO Caihua
SU Qin
CHEN Yi
Abstract：Objective To explore the clinical significance of flow reserve fraction based on coronary artery CT angiography(CT-FFR)in the diagnosis and treatment of coronary artery disease(CHD).Methods A retrospective study was conducted on 87 patients who underwent coronary artery CTA(CCTA)examination in our hospital.The eligible vessels were screened,the de-gree of stenosis was evaluated,and the images were imported into the digital AI software to analyze the CT-FFR value.Revascu-larization was recommended for patients with CT-FFR<0.75or coronary CTA stenosis(≥50.0%),drug maintenance was recom-mended for CT-FFR≥0.75 or less than moderate coronary stenosis(stenosis<50.0%).The patients accepted clinical decisions were followed up,and the clinical guiding value of coronary artery CTA and CT-FFR for coronary artery disease was compared.Results 136 vessels were selected for revascularization(stent implantation or bypass surgery)in 27 cases/48 vessels and drug maintenance therapy in 60 cases/88 vessels.The sensitivity of CT-FFR method was 75.0%,and the specificity was 92.1%.The sensitivity of coronary CTA method was 79.2%,and the specificity was 60.2%.There was no significant difference in sensi-tivity between the two methods(P<0.001).Conclusion CT-FFR has independent predictive value for myocardial ischemia and can guide clinical decision-making.
Keywords：Blood flow reserve fractionTomographyX-ray computedCoronary artery disease
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 2191-2195 )