Correlation analysis between T2 value of left ventricular myocardium and left cardiac function in patients with type 2 diabetes mellitus

FENG Genyi; ZHANG Lei; LI Jinsong; HE Chao; WANG Jiangang; HU Qing; ZHAO Zhiming; ZHU Guobin; HUI Yating

Abstract：Objective To explore the correlation between the mean T2 value of the left ventricular myocardium and the left cardiac function,and to evaluate the clinical value of T2-mapping imaging in patients with type 2 diabetes mellitus(T2DM).Methods 92 T2DM patients with symptoms and signs of typical cardiac failure(study group)and 30 healthy adults(control group)were selected.According to the cardiac function classification of New York Heart Association(NYHA),T2DM group was classified as NYHA Ⅰ-Ⅱ group(54 cases),NYHA Ⅲ-Ⅳ group(38 cases).All patients underwent cardiac magnetic resonance im-aging(CMRI),T2-mapping imaging,and ultrasonic cardiogram(UCG)examination.The correlation between the mean T2 value of the left ventricular myocardium and the left cardiac function in the T2DM group was analyzed.Result There was no statistical difference between CMRI and UCG results of the left cardiac function in the study and control groups(P>0.05).The mean T2 value of the left ventricular myocardium in each T2DM subgroup was greater than that in the control group(P<0.01),and the T2 value increased with the increase of NYHA cardiac function classification(P<0.01).The mean T2 value of left ventricular myo-cardium in T2DM group was significantly negatively associated with left ventricular diastolic function(P<0.01),and the left ven-tricular diastolic function in T2DM group was lower than the control group(P<0.01).The mean T2 value of the left ventricu-lar myocardium was significantly negatively associated with left ventricular systolic function(P<0.01),but no statistical differ-ence in left ventricular systolic function between the grade NYHA Ⅰ-Ⅱ group and control group(P>0.05).Conclusion There was a close correlation between T2 value of the left ventricular myocardium and left cardiac function of patients with T2DM,which can be used to predict the risk of left ventricular failure in patients with T2DM.