Optimization of CT guided percutaneous aspiration biopsy in pulmonary sub-centimeter nodule

SU Lei; DONG Junqiang; HU Lili; ZHOU Zhigang; GAO Jianbo

Abstract：Objective To compare the biopsy effect of combined use of 17 G coaxial biopsy gun and optimization of CT guided percutaneous biopsy technique with traditional 18 G application in the patients with sub-centimeter pulmonary nodules (sPN). Methods Study group: 78 cases of sPN were obtained by using 17 G coaxial biopsy gun and optimization of CT guided percutaneous biopsy technique and pathologically confirmed. Control group: 54 cases of pathological confirmed sPN were obtained by applying 18 G biopsy needle and rotary cutting aspiration biopsy. The comparison of categorical data was performed by using t test or Wilcoxon Rank-Sum test. The qualitative data were compared by chi-square test. Results There were 41 benign, 34 malignant and 3 negative cases in the study group and 16 benign, 22 malignant and 16 without pathological results cases in the control group. The average completion time in the study group (18.03±8.08) min is shorten than control group (22.31±7.55) min. Significant differences in the positive rate and the bleeding complications were found between the study group (96.15％, 26.92％) and the control group (70.37％, 35.18％) (P=0.041, 0.000, 0.045). Conclusion Combined use of coaxial tube biopsy gun and optimization of CT guided puncture biopsy technique to puncture the lung sub centimeter nodulescould increase the accuracy rate and the positive rate the biopsy and shorten the biopsy time.