Spectral CT imaging in the evaluation of status of lymph nodes in laryngeal and hypopharyngeal squamous cell carcinoma
HU Lei
LUO Dehong
LI Lin
YANG Liang
LIN Meng
ZHAO Yanfeng
ZHAO Xinming
ZHOU Chunwu
Abstract：Objective To evaluate the value of spectral CT parameters in differential diagnosis of metastatic lymph nodes and non-metastatic lymph nodes in laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC). Methods Seventy-three patients with pathologically proven LHSCC (42 cases of metastatic group and 31 cases of non-metastatic group) underwent contrast-enhanced energy spectral scan. The λHu-P, λHu-L, and λHu were compared between metastatic and non-metastatic groups. Results The λHu-L was (2.5±0.7) and (2.1±0.7), respectively, and the difference was statistically significant (P=0.037). No significance of λHu-P was observed between metastatic and non-metastatic groups (P=0.177). The λHu were (1.09±0.38) and (0.81±0.25), respectively, and the difference was statistically significant (P=0.001). Setting λHu value of 0.86 as threshold to distinguish metastatic and non-metastatic lymph nodes, the AUC, sensitivity and specificity were 0.773, 83.3％, 77.4％, respectively. Conclusion Spectral CT parameters might contribute to the differential diagnosis of cervical lymph nodes in LHSCC.
Keywords：Laryngeal and hypopharyngeal squamous cell carcinomaLymph node metastasisTomographyX-ray computed
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 363-367 )