1H-MRS study on hippocampus in the patients with postpartum depression
HUANG Xiaoyan
GU Xiaoli
SHEN Xiaoyong
SHAO Yongliang
Abstract：Objective To study the characteristic of 1H-magnetic resonance spectroscopy (～1H-MRS) on hippocampus in patients with postpartum depression (PPD). Methods 63 patients with PPD and 30 volunteers were scanned on a 1.5 T magnetic resonance scanner. The region of interest was placed on the hippocampus bilaterally, and the value of NAA/Cr, Cho/Cr was counted. Results The bilateral hippocampus NAA/Cr ratio was lower in moderate and severe PPD group compared with healthy control subjects and mild PPD group respectively (P＜0.05). There was no statistically significant difference on Cho/Cr ratio between the normal group, the mild PPD group and the moderate and severe PPD group (P＞0.05). Conclusion The change of NAA level in hippocampus is closely related to the occurrence of postpartum depression.
Keywords：Postpartum depressionHippocampusMagnetic resonance imaging1H magnetic resonance spectroscopy
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 184-186 )