18F-FDG PET/CT imaging features of inflammatory myofibroblastic tumor

HUANG Wei; WU Liling; LI Hongfei; SHEN Fuyu; Ding Chongyang

Abstract：Objective To evaluate the 18F-FDG PET/CT imaging features of inflammatory myofibroblastic tumor (IMT) ,so as to improve its diagnostic accuracy. Methods The clinical and 18F-FDG PET/CT imaging findings of 7 cases of IMT which were confirmed by pathology in our hospital were analyzed retrospectively,including 2 males and 5 females,aged from 16 to 79 years old,median age was 57 years old. Results Of the 7 cases with 20 lesions of IMT,5 had a single lesion,and 2 cases had multiple ones. Of the 5 cases with single lesion,3 cases located in lung,1 case located in crus and 1 case located in pelvic cavity. Of the 2 cases with multiple lesions,1 case had involved mediastinum,abdomen and pelvic wall,and 1 case had involved the abdominal wall and pelvic wall. 15 lesions were appeared as round or oval soft tissue density node or mass,5 lesions were appeared as irregular with lobulated. Most of the lesions were uniformly dense with clear boundary. The SUVmax of all lesions was 13. 1(5. 9,19. 5) ,the maximum diameter was 2. 6(2. 0 ～ 4. 4) cm. There was no correlation between SUVmax and the maximum diameter (r=0. 411,P=0. 072). The Ki-67 was detected in 5 cases,there was positive correlation between SUVmax and Ki-67(r=0. 794,P=0. 001). Conclusion The 18F-FDG PET/CT imaging features of IMT are lack of specificity. But the 18FFDG uptake of lesion can be used in predicting tumor malignancy.