Evaluation of left ventricular systolic function in coronary heart disease with real-time three-dimensional speckle tracking

HUANG Weifei; LIN Xianfang; YANG Linxian

Abstract：Objective To observe the effect of real-time three dimensional speckle tracking technique for evaluating the left ventricular systolic function in coronary heart disease patients without regional wall motion abnormality. Methods 120 cases of suspected coronary heart disease without regional wall motion abnormality were selected in our hospital from January 2015 to May 2016, these cases were divided into 2 groups according to angiography, three main artery at least one of coronary artery stenosis≥50% were selected as the observation group (n=73), and three main artery of coronary artery stenosis <50% were selected as the control group (n=47). Using real-time three dimensional speckle tracking technique, we measued 2 groups of global longitu-dinal strain value, global circumferential strain value, global radial strain value, global area strain value in left ventricular, and measured 2 groups of longitudinal strain value, circumferential strain value, radial strain value. SPSS 18. 0 software was used to analyze the data. We drew ROC curve and then calculated the optimal cut-off value, sensitivity and specificity of all global strain value. We studied the effect of the correlation between the different parameters, checked the consistency between the parameters and LVEF, compared the difference between the interobserver and the intraobserver. Results GLS, GRS, GCS and GAS in left ventricular using real-time three-dimensional speckle tracking in observation group, were significantly lower than the control group ( P <0. 05); ROC curve showed that GAS had higher sensitivity and specificity. When optimal cut-off value of GAS was -28. 3%, sensitivity was 78. 3% and specificity was 67. 5%. LVEF was negatively correlated with GAS, GCS and GLS ( P <0. 05);LVEF was positively correlated with GRS ( P <0. 05). Conclusion Real-time three-dimensional speckle tracking tech-nology can comprehensively and accurately detect left ventricular global and regional systolic function in early coronary heart dis-ease patients without regional wall motion abnormality.