Study of SPECT in patients with crossed cerebellar diaschisis after cerebral infarction

HOU Yaqin; LU Jie; CAO Yanxiang; ZHANG Haiqin; GUAN Le; SHUAI Dongmei; LIANG Zhigang

Abstract：Objective To explore the changes of cerebral perfusion and glucose metabolism in patients with crossed cerebellar diaschisis (CCD) after supratentorial unilateral cerebral infarction using single photon emission tomography(SPECT). Methods Thirty CCD patients after cerebral infarction underwent SPECT 99mTc-ECD cerebral blood perfusion and glucose metabolism ima-ging. SPECT images were performed qualitative and quantitative analysis. The correlation of cerebral blood perfusion and glucose metabolism asymmetry index(AI) between supratentorial cerebral region and contralateral cerebellum were analyzed. The correla-tion between the infarction volume and cerebral blood perfusion and glucose metabolism AI of contralateral cerebellum was also an-alyzed. Results SPECT demonstrated cerebral blood perfusion and glucose metabolism decreased of multiple cerebral regions in patients with CCD. The most involved cerebral region was the frontal lobe. The AI of cerebral blood perfusion between supratento-rial cerebral region and contralateral cerebellum had positive correlation ( P <0.01). However,there had no correlation of glu-cose metabolism AI between supratentorial cerebral region and contralateral cerebellum ( P >0.05). There also had no correla-tion of infarction volume(25.87 ± 16.43) cm3and cerebral blood perfusion and glucose metabolism AI of contralateral cerebellum ( P >0.05). Conclusion SPECT could demonstrate the changes of cerebral blood flow and glucose metabolism, and evaluate the relationship between cerebral blood flow and abnormal glucose metabolism and CCD.