Application value of 1. 0T open MR-guided percutaneous peri-pulmonary lesion biopsy and analysis of complications re-lated factors from 405 cases

LI Peipei; LIU Ming; WANG Ligang; GUO Zongtong; XU Yujun; HE Xiangmeng; WANG Qingwen; LI Chengli

Abstract：Objective To retrospectively evaluate the feasibility, safety and accuracy of 1. 0 T open magnetic resonance ima-ging ( MRI)-guided percutaneous cutting needle biopsy of peripheral pulmonary lesions. Methods We retrospectively analyzed 405 cases underwent MR-guided percutaneous biopsy of peripheral pulmonary lesions in our department. Using Fisher's exact test, we compared the diagnostic accuracy of two different groups (≤2 cm and >2 cm) in different diameters, calculated the incidence of complications such as pneumothorax, hemoptysis, hemothorax, and analyzed the related factors of various complications. Re-sults The accuracy, specificity and sensitivity of MR guided percutaneous percutaneous biopsy in the diagnosis of malignant tumors were 96. 30%, 100% and 95. 13%, respectively. The diagnostic accuracy, specificity and sensitivity of the lesions were 95. 51%, 100%, 92. 92% and 96. 92%, 100% and 96. 17% respectively in the two groups. There was no statistically signifi-cant difference ( P >0. 05). The average puncture time was (25 ± 7) minutes (range 17~40 minutes). MR-guided percutane-ous lung biopsy-related complications:the incidence of pneumothorax was 7. 6%, closed thoracic drainage was 1. 5%; the inci-dence of intra-pulmonary hemorrhage was 23%, hemoptysis was 4. 7%, blood chest was 0. 2%, no other serious complications occurred. Long pulmonary parenchymal puncture path (≥4 cm) was the related risk factor of pneumothorax, and small lesion size (≤2 cm) and long puncture path (≥4 cm) were the related risk factors of pulmonary hemorrhage. Conclusion 1. 0 T open MR-guided percutaneous biopsy is an accurate and safe diagnostic technique for the diagnosis of peripheral pulmonary le-sions. Long puncture path is the related risk factor of pneumothorax, and small lesion size and long puncture path are the related risk factors of pulmonary hemorrhage and hemoptysis.