Application of acoustic radiation force impulse imaging in differentiation of thyroid nodules
WANG Pei
FENG Aifen
Abstract：Objective The aim of this study was to evaluate sensitivity and specificity of acoustic radiation force impulse ima-ging ( ARFI) in differentiation of thyroid nodules. Methods ARFI features of 138 thyroid nodules were analyzed. The VTI fea-tures were divided into 4 types. Virtual Touch tissue quantification ( VTQ) was used to quantitatively analyze the elasticity and hardness of nodules. Results VTI-black or cellular sample was used as the diagnostic criterium of malignancy. The sensitivity, specificity and accuracy rate in differentiation between benign and malignant thyroid nodules were 93. 8%, 76. 7% and 82. 6%respectively. The Vm and Vrate of the malignant nodules showed statistically significant differences compared with those of the be-nign nodules ( P <0. 05). According to ROC curve the best diagnostic critical point of Vm and Vrate was 2. 75 m/s and 1. 32 re-spectively;The areas under ROC curve of VTQ were 0. 851 and 0. 799 respectively. Conclusion Acoustic radiation force im-pulse imaging has high sensitivity and specificity in evaluating benign and malignant thyroid nodules and there is a high diagnostic value in clinical applications.
Keywords：Acoustic radiation force impulseThyroid noduleSonography
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1671-1675 )