Initial study of dynamic evaluation of salivary gland function by magnetic resonance diffusion weighted imaging
PAN Caizhu
YANG Ling
CHEN Bijuan
XIAO Youping
LI Minfeng
Abstract：Objective To observe the dynamic changes in MR-DWI ADC values of parotid and submandibular gland before and after acid stimulation, and to further explore the feasibility of MR-DWI in salivary gland function evaluation. Methods A to-tal of 10 healthy volunteers in Fujian provincial tumor hospital between July and August 2011 were recruited, MR-DWI scanning was done at different time periods before and after acid stimulation for each patient, then the ADC values of salivary glands were recorded. The changes of MR-DWI ADC value of parotid and submandibular gland before and after acid stimulation were ana-lyzed. Results In 10 patients, the ADC value of parotid gland and submandibular gland in resting state was (0. 95 ± 0. 06) × 10-3 mm2/s and (1. 20 ± 0. 10) × 10-3 mm2/s, respectively. The ADC value of salivary gland was increased in first 3 minutes after acid stimulation, then decreased at 6th minute, and then increased gradually to the peak level at 15th~21st minutes, and then gradually declined to resting levels. Conclusion MR-DWI can noninvasively evaluate the dynamic physiologic changes of salivar-y glands before and after acid stimulation.
Keywords：Salivary glandFunction evaluationMagnetic resonance diffusion weighted imaging
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1665-1667 )