Character of imaging and follow-up examination in persistent ground-glass opacities on CT scan

CHAI Wenyi; JIA Shujie; CHEN Wufei; MAO Dingbiao

Abstract：Objective To analyze the value of baseline CT manifestations and follow-up examination in persistent pulmonary ground-glass opacity (GGO) with different pathological types.Methods Baseline CT features and changes during follow-up of 51 patients with 51 lesions who underwent curative resection from March 2011 to March 2016 were retrospectively analyzed.Follow-up period lasted at least 3 months for each patient.All lesions were divided into benign and malignant groups according to the international multidisciplinary classification of lung adenocarcinoma.Results 51 cases in the group included 17 cases of benign lesions and 34 cases of malignant Lesions.There were no statistical differences in CT features between two groups,however,statistical difference of sizes in the ranges of 5 ～ 10 mm and 11 ～ 15 mm was significant.Follow-up time of malignant group was longer than the benign group.2 cases of benign group changed in CT features based on baseline CT scan.18 cases changed in malignant group.Data were significantly different on the change ratio between two groups.Conclusion There is no definite specificity of CT features on baseline CT scan of persistent GGO.Size can be one of the reference for the differentiation between benign and malignancy nodules.Follow-up management is an important mean for this kind of lesions.An appropriate follow-up examination can provide an important point of reference in differential diagnosis.