Searching for the reasonable patient preparation protocol for heart and pericardium lesions of patients
SHAO Dan
GAO Qiang
WANG Shuxia
WANG Siyun
LIU Entao
Abstract：Objective Myocardial 18F-FDG uptake in PET scans in patients prepared by the usual fasting protocol may result in difficulties in interpretation because variable uptake may yield false-positive results regarding mediastinal abnormalities.We aimed to analyze, retrospectively, the effect of diet on myocardial FDG uptake.Methods A total of 50 patients who adhered to two meals before PET/CT scanning that were prepared using a low carbohydrate, high fat and protein-permitted diet, were compared with 50 patients who fasted for at least 12 hours prior to scanning.The differences of SUVmax of myocardium between "fasting" group and the "new diet" group were analyzed by Mann-Whitney U Test (Non-normal distribution).Results The SUVmax of the "fasting" group was 4.6±4.0, and the SUVmax of the "new diet" group was 1.9±0.9.This showed significant difference by Mann-Whitney U Test (Z =-6.348, P=0.000).Conclusion A very high-fat, low-carbohydrate, protein-permitted diet before FDG injection suppresses myocardial FDG uptake.This should facilitate definition of mediastinal abnormalities on FDG PET.It is a more reasonable patient preparation protocol for the patients with heart and pericardium lesions.
Keywords：Cardiac imagingpatient preparation protocolTomographyX-ray computedPositron emission tomography
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1239-1242 )