Correlation between hyperintense vessels on FLAIR imaging and time to peak on cerebral CT perfusion
ZHANG Zhiguo
WU Chuanhua
YOU Kezeng
Abstract：Objective To investigate the relationship between hyperintense vessels (HVs) on fluid-attenuated inversion recovery (FLAIR) and Time to Peak (TTP) on Cerebral CT Perfusion (CTP).Methods We retrospectively reviewed 46 patients with proximal middle cerebral territorial infarction who underwent MR Imaging and CT perfusion, and calculated the difference in TTP(ΔTTP) and mean transit time (ΔMTT) between infarcted and normal hemispheres.We scored HVs on FLAIR imaging using a modified Alberta Stroke Program Early Computerized Tomography Score (ASPECTS).Spearman correlation analysis was used to explore the relationship among the FHV score and CTP parameters.Results We detected HVs on FLAIR images in 38 patients (median score, 4;range, 0 to 7).Comparison of infarcted and normal hemispheres demonstrated absent HVs on FLAIR imaging when the ΔTTP was too short (<one second).HVs scores on T2-FLAIR showed a significant positive correlation with ΔTTP (r=0.748,P<0.001), while ΔMTT showed moderate significant relationship (r=0.338,P=0.021).Conclusion In cases of large arterial occlusion, ΔTTP and T2Flair HVs have good correlation,the hyperintensity of vessels on FLAIR images may be dependent on retrograde filling time of the leptomeningeal collateral circulation.
Keywords：Collateral circulationHyperintense vesselTomographyX-ray computedMagnetic resonance imaging
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1218-1220,1228 )