Value of 99mTc-MIBI double-phase and SPECT/CT fusion imaging in diagnosis of primary hyperparathyroidism
LI Jun
LI Li
Lin Hua
Abstract：Objective To evaluate the clinical value of 99mTc-MIBI double-phase and SPECT/CT fusion imaging in diagnosis of primary hyperparathyroidism (PHPT).Methods This study included 20 patients with PHPT.99mTc-MIBI double-phase and SPECT/CT fusion imaging were done in all cases.The imaging fingdings were compared to the pathological results.The sensitivity of two inspection methods was calculated and compared.Results 20 patients (28 lesions) with PHPT were properly diagnosised with postoperative pathology.There were 16 cases (21 lesions) of parathyroid adenomas, 2 cases (5 lesions) of parathyroid cysts, 1 case (1 lesion) of ectopicthyroid adenoma and 1 case (1 lesion) of parathyroid carcinoma postoperative lymphatic metastasis.The sensitivity of 99mTc-MIBI double-phase was 64.3%, and the sensitivity of SPECT/CT fusion imaging was 85.7%, and the diagnostic sensitivity of SPECT/CT was higher than that of 99mTc-MIBI double-phase (P<0.05).Conclusion 99mTc-MIBI SPECT/CT fusion imaging is an effective method for diagnosis of PHPT, and with higher clinical application value in the diagnosis of patients with PHPT than 99mTc-MIBI double-phase.
Keywords：Primary hyperparathyroidismTechnetium (99mTc) sestamibiSingle photon emission computed tomogmphy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1063-1067 )