Analysis of quantitative MRI and ultrasound in qualitative diagnosis of benign and malignant thyroid nodules

ZHANG Feng; LI Ping; YAO Jian

Abstract：Objective To investigate the value of ADC, FS-T2WI signal intensity ratio (SIR) threshold in the quantized magnetic resonance imaging and ultrasound imaging characteristics of benign and malignant thyroid nodules.To compare and analyze the diagnostic value of the qualitative diagnosis of thyroid nodules.Method This study included 20 patients clinically diagnosed with thyroid nodules.A total of 28 solid thyroid nodules, including 14 benign nodules and 14 malignant nodules.All were examined by ultrasound, magnetic resonance T1WI, FS-T2WI and diffusion weighted imaging (b value 0, 300 s/mm2).The T2 signal intensity ratio (SIR) of each thyroid nodule was calculated.The threshold range of apparent diffusion coefficient (ADC) of benign and malignant nodules.The T2WI signal intensity ratio (SIR), ADC value and nodules on conventional magnetic resonance imaging features in determining the best diagnostic criteria for magnetic resonance imaging of benign and malignant nodules, and compared with the results of ultrasound in qualitative diagnosis of nodules.To analyze the value of magnetic resonance imaging and ultrasound in the diagnosis of benign and malignant thyroid nodules.Results The mean T2 SIR (P<0.05) and ADC (P<0.05) were significantly higher for benign nodules than for Malignant nodule.The sensitivity and specificity was 100% and 85.71%, on T2 SIR;were 100%, 84.62%, on ADC;were 100%, 92.86%,on combined T2SIR and ADC.The sensitivity and specificity of ultrasound in the diagnosis of benign and malignant thyroid nodules were 92.86% and 64.29%, respectively.Conclusion Magnetic resonance imaging and ultrasound have certain advantages in the diagnosis of benign and malignant thyroid nodules.FS-T2WI signal intensity ratio (SIR) and ADC value in the diagnosis of benign and malignant thyroid nodules were more accurate in magnetic resonance imaging.