MRI appearance of marechiafava-bignami disease involving extracallosal lesions
WU Jie
WANG Xuejian
SONG Lingling
ZHANG Tijiang
XIAO Hui
SUI He
WU Zhongchun
LIU Ying
Abstract：Objective To investigate the appearance of marechiafava-bignami disease (MBD) affect extracallosal. MethodsMR findings of 68 patients in marechiafava-bignami disease with bilateral extracallosal lesions were retrospectively analyzed. Results Acute onset (n=28), subacute onset (n=17), and choronic onset (n=23) were found in the 68 cases.All patients showed symmetrical signal abnormality in the corpus callosum and both hemispheric white matter,cortical gray matter, middle cerebellar peduncles, posterior internal capsule, and anterior commissure.MRI revealed iso-or hypo-intensity on T1WI, hyper intensity on T2WI and FLAIR and DWI.There were the same intense signals in both corpus callosum and ertracallosal.DWI showed equal bright signal intensity located in the corpus callosum and hemisphere white matter.Conclusion Extracallosal affected areas in MBD were probably demonstrated by MR image during the acute exacerbation phase.MR imaging is helpful in early diagnosis and management of MBD.
Keywords：Marechiafava-bignami diseaseExtracallosalmagnetic resonance imaging
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 591-595 )