Correlative analysis of microsatellite location and risk stratification in single-focal thyroid with ultrasonography

ZHANG Yanru; XU Dong; XING Peihua; HE Boqin; FEI Zhiqun; CHENG Keling

Abstract：Objective To investigate the effect of ultrasonography on microcarcinoma of thyroid in single foci, and to analyze the correlation between microcarcinoma of thyroid and cervical lymph node metastasis.Methods The clinical data of 80 cases (80 nodules) in our hospital were retrospectively analyzed.All the patients were examined by ultrasonography.The patients were divided into two groups according to the presence of lymph node metastasis, experimertal group (lymph node metastasis, 40 cases) and the control group (cervical lymph node metastasis, 40 cases).The sonographic findings were recorded and compared with postoperative pathologic findings.The correlation was also found.Results The analysis showed that the nodules form (OR2=0.95, P=0.32), cancer nodules internal echo (OR2=0.72, P=0.39), cancer nodules boundary (OR2=1.26, P=0.25), rear echo nodules (OR2=0.73, P=0.39), cancer nodules surrounding echo (OR2=0.95, P=0.32), cancer nodules position (OR2=0.44, P=0.93), and single lesion type of thyroid microcarcinoma of cervical lymph node metastasis, P<0.05, patients in study group and control group cancer nodules (OR2=25.08, P=0.00), the relationship between cancer nodules and films (OR2=25.84, P=0.00), calcification type cancer nodules (OR2=19.52, P=0.00) were significant difference statistical significance, P<0.05;through the analysis of multiple regression Logistic, we found that cervical lymph node metastasis and cancer nodules (OR=5.721, P=0.00), cancer nodules and thyroid capsule (OR=4.961, P=0.00), the relationship between cancer nodules and calcification type were correlated (OR=4.689, P=0.00) on, P<0.05.Conclusion Ultrasonography can be used to diagnose small thyroid microcarcinoma of the foci by judging whether there is cervical lymph node metastasis by observing clinical ultrasonography, which can be helpful for clinical diagnosis and treatment, and provide reference for clinical treatment plan and prognosis judgment.