Preliminary study of MRS in dorsolateral prefrontal cortex of patients with anxiety after radiofrequency catheter ablation
TANG Xiaoli
ZHENG Hairong
JIN Jun
LV Guiwen
MO Xin
CAO Jinbo
Abstract：Objective Patients with arrhythmia after radiofrequency catheter ablation exist anxious state.At present, the pathogenesis is unclear.MRS technique is used to observe the change of metabolites in the dorsolateral prefrontal cortex.Methods In this study, 32 patients with anxiety disorder after radiofrequency catheter ablation were included as RFCA group.Age and sex matched thirty-two healthy volunteers were included as control group.Results In the left prefrontal cortex, the ratio of Cho/Cr was significantly lower in the RFCA group (0.71±0.16) than in the control group (0.87±0.14) (P=0.022, z=2.364).The ratio of Cho/Cr was significantly lower in RFCA group (0.73±0.12) than that in control group (0.84±0.15) (P=0.019, z=2.304) in the right prefrontal cortex.The ratio of other metabolites was not statistically significant (P>0.05).Conclusion Patients present with anxiety after radiofrequency ablation;the decrease in Cho levels in the dorsal lateral cortex of the prefrontal cortex may reflect the neuronal damage and potential cognitive dysfunction in pathological anxious condition, so as to provide more evidence for the pathogenesis of the disease.
Keywords：Radiofrequency catheter ablationAnxietyMagnetic resonance imagingDorsal lateral cortex of the prefrontal cortex
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 422-425 )