Resting-state fMRI studies in basal ganlia stroke patients by dgree centrality analysis
WANG Hui
CHEN Nan
LI Kuncheng
DUAN Xianggong
Abstract：Objective To study the changes of degree centrality (DC) of the resting-state fMRI in basal ganlia stroke.Methods The resting-state fMRI data of 10 ischemic stroke patients with left basal ganllia area lesion under subacute stage, chronic phase and 10 normal controls were taken.The three groups of data were performed DC analysis.Results Compared with normal controls, in subacute stage, DC increased in contralateral precuneus, superior parietal lobule and superior temporal gyrus, decreased in the ipsilateral middle and superior frontal gyrus, in chronic phase, DC increased in vermis, contralateral precuneus and posterior cingulated, compared between two stages of the patients, in vermis, contralateral cerebellar hemispheres and ipsilateral precuneus, DC was higher under subacute stage, in ipsilateral precentral gyrus, superior temporal gyrus and supramarginal, DC was higher under chronic phase.Conclusion Based on graph theory, DC can investigate the whole-brain functional networks in the voxel-wise, It might be an appealing alternative approach for further study the adaptive reorganization of brain function and network architecture change after stroke.
Keywords：Ischemic strokeDegree centralityMagnetic resonance imagingGraph theory
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 393-396 )