Myocardial native T1 and T2 mapping at 3.0 T in a healthy group with same age

WANG Junli; ZHAO Bin; WANG Bao; WANG Haipeng; SHEN Yelong

Abstract：Objective To dats no studies of myocardial native T 1 and T2 mapping in healthy groups with same age have been out carried previously .This article aims to reveal variability and gender difference of them for the first time .Methods For this retrospective study , 3025-year-old healthy volunteers were recruited undergoing left ventricular native T 1 and T2 mapping in 3 short-axis slices at 3 T.For T1 mapping, modified Look-Locker inversion recovery technique with 11 single shot SSFP images was used.For T2 mapping, 3 single-shot steady-state free precession ( SSFP) images with different T2 preparation times were ac-quired.T1 and T2 relaxation times were quantified for each slice and each myocardial segment .Results Mean native T1 and T2 times (T1/T2) were 1274.1 ms/36.5 ms (base), 1273.2 ms/37.4 ms (middle), 1297.8 ms/38.2 ms (apex) and coefficient of variability (%) (T1/T2) were 2.9/4.2 (base), 2.7/4.3 (middle), 3.6/5.5 (apex).Significant gender difference was found in global and each slice (each P <0.01) of both T1 and T2 mapping.Conclusion Establishing a normal reference of myo-cardial T1 and T2 mapping in accordance with age and gender , which is a much more precise reference for the clinic , can help cli-nicians distinguish nidi from normal myocardium more effectively .For the researches of myocardial T 1 and T2 mapping technique in the future, the control group (healthy group) should take into account of the age distribution and gender difference as always .