2 Clinical application of dual-CT in the effect of anticoagulation on the remodeling of residual lumen after aortic valve re-placement of DeBakey type I aortic dissection

LI Yuanyuan; WANG Long; DUAN Yanhua; CHENG Zhaoping; LIU Yanping; CHEN Baojin; WANG Ximing

Abstract：Objective To investigate the clinical application of low dose retrospective ECG-gated CTA in the effect of antico-agulation on the remodeling of residual lumen after aortic valve replacement of DeBakey type I aortic dissection .Methods A to-tal of 30 patients with DeBakey type I aortic dissection underwent ECG-gated double source CTA .Those patients were divided into two groups, group A(n=19) who underwent surgical repairs with total arch replacement and modified stented elephant trunk tech -nique (Sun's Operation) and, group B(n=11), who underwent surgical repairs with Sun 's Operation and aortic valve replace-ment.About 3 to 6 months after surgery, aortic CTA examination was obtained , the diameter of the true lumen and aorta in the level of the celiac trunk , superior mesenteric artery and renal artery in each phase were measured .The pre-operative and postoper-ative ratio of true lumen and aorta were calculated and the remodeling of residual lumen indirectly was compared .Results The age, the incidence of hypertension and coronary heart disease in patients with non -valve replacement group were higher than the valve replacement group ( P =0.004, 0.001, 0.023).But in the incidence of Marfan's syndrome , the results were reversed ( P =0.003).There was no significant difference in the preoperative and postoperative ratio of the true lumen and aorta diameter in the three levels between the two groups .Conclusion Whether the aortic valve is involved , there has no difference in the remode-ling of residual lumen .Low dose retrospective ECG-gated double source CTA provides high diagnostic accuracy for the remodeling of residual lumen after aortic valve replacement of DeBakey type I aortic dissection .