The value of combined use of 3D arterial spin-labeled perfusion imaging and 3D susceptibility weighted angiography in a-cute cerebral infarction
CHEN Feng
ZHANG Guanghui
LI Zhongwei
WANG Aijie
LIANG Hui
WANG Ying
ZHANG Guowei
Abstract：Objective To study retrospectively imaging features of 3D arterial spin labeling (ASL) perfusion imaging and 3D susceptibility weighted angiography ( SWAN) of acute cerebral infarction ( ACI) , and to investigate further the guiding value of combined use of 3D ASL and 3D SWAN in thrombolytic therapy .Methods Conventional MRI scan , DWI, MRA, 3D ASL and 3D SWAN were performed in 63 patients with ACI by using 3.0 T MR scanner.Two experienced neuroradiologists evaluated inde-pendently and separately imaging findings of DWI , MRA, 3D ASL and 3D SWAN of the ACI.Results ASL-CBF perfusion maps showed decreases of cerebral blood flow in 52/63 patients with ACI , the size of hypoperfusion on ASL was larger than high signal intensity on DWI in 38/52 patients.Thrombosis within middle cerebral artery was shown by SWAN in 16/52 patients with hy-poperfusion on ASL .Hyperperfusion was observed on ASL in 11/63 patients .Signs of hemorrhage within and/or around hypoper-fusion areas were detected by SWAN in 16/63 patients (12 patients with hypoperfusion and 4 patients with hyperperfusion in ASL-CBF).Conclusion The combined use of 3D ASL and SWAN can not only evaluate cerebral perfusion features and the thrombo -sis of the responsible arteries of the ACI , but also detect risk factors for potential bleeding , which has important clinical utility in guiding the thrombolytic therapy for ACI patients .
Keywords：Acute cerebral infarction3D arterial spin labelingSusceptibility weighted imagingMagnetic resonance imaging
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 25-28 )