Application of dual-source CT iodine map and energy spectrum curve technique in differential diagnosis of th yroid nod-ule

JIN Mei; LIU iL; LIN Yijun; GAO Zhenxing; CHEN Tong; HOU Qinggeng; XU Guirong; YU Xiaoming; GU Yue

Abstract：Objective To explore the clinical utility of dual-source CT iodine map and energy spectrum curve technique which are used in differential diagnosis of thyroid nodule .Methods The radiographic data of fifty-eight cases confirmed by pathology were retrospectively analyzed in parallel normal Thyroid and Dual energy patterns ( DECT ) of patients with Thyroid nodule en-hancement scanning , using the iodine map and energy spectrum curve , which processed by the “Liver VNC”and “Monoenergyt-ic”.We campared the thyroid nodules iodine map and energy spectrum curve display of the lesions .Results Lodine content of the benign nodules was significantly lower than that of the normal thyroid tissue but higher than that of the malignant nodules , there was a significant difference in the contents of iodine in the solid components between bengin and malignant thyroid nodules ( P <0.05 ) .In benign group , all nodules single spectral imaging lesion solid composition showed the decline type curve , consist-ent with normal thyroid tissue energy spectrum contorts , an upward curve in malignant group , a small number of performance de-cline type curve .Benign group of curve slope in the three phase phase were greater than malignant group , in the scan and arterial , curve slope of two comparison of the differences between two groups had statistical significance ( P <0.05).The sensitivity of dual energy CT examination was 85.5%, specificity was 92.9%, the accuaracy was 96.2%.Conclusion The accuracy of qual-itative diagnosis of thyroid nodules improved by quantitative analysis of joint iodine map and energy spectrum curve technique has obviously provided the important information for clinical therapy of thyroid gland .