Comparative study of arterial spin labeling and dynamic susceptibility contrast enhanced perfusion weighted imaging in neuromyelitis optica
SUN Zheng
DUAN Yunyun
HUANG Jing
LIU Yaou
REN Zhuoqiong
ZHANG Tian
LI Kuncheng
Abstract：Objective To compare the difference between arterial spin labeling ( ASL ) and the dynamic susceptibility con-trast-enhanced perfusion weighted imaging ( DSC-PWI) for assessing brain perfusion in neuromyelitis optica ( NMO) patients. Methods ASL and DSC-PWI data were acquired from 10 cases of NMO.Cerebral blood flow (CBF) of fourteen regions of inter-est (ROI), including caudate nucleus , putamen, thalamus and white matter in the frontal lobe , parietal lobe, temporal lobe and occipital lobe , were measured using siemense postprocessing station .Results There was no significant difference between the two techniques.( t =1.061, 0.496, 1.312, -0.342, -0.403, -0.156, 0.224;P =0.329, 0.637, 0.238, 0.744, 0.708, 0.881, 0.830).There were significant correlations between CBF measured by ASL and that by DSC ( r =0.659, P =0.000), except for the ROI in parietal lobe .Conclusion Non-invasive ASL perfusion is as sensitive as DSC-PWI in evaluating NMO , and can be used in the clinical assessment .
Keywords：Neuromyelitis opticaArterial spin labelingDynamic susceptibility contrast-enhanced perfusion weightedCere-bral blood flow
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 2145-2149 )