Clinical application value of 3D-A SL and DWI in cerebrovascular o cclusion diease

JI Yu; SHAO Guangrui; MA Shuai

Abstract：Objective To explore value of 3D arterial spin labeling (3D-ASL) imaging and diffusion weighted imaging ( DWI) in the diagnosis of cerebrovascular occlusion diease.Methods A total of 30 cases with cerebral infarction in 20 case and transient ischemic attack ( TIA) in 10 case were included in this study.They were all one or more cerebral vascular occlusion in MRA.All subjects underwent T1 WI, T2 WI, DWI, 3D-ASL scanning.We respectively measured ASL perfusion abnormal area and DWI lesions.The results were analyzed by paired t-test.Then, all patients were classified into ASL>DWI group, ASL≈DWI group and ASL<DWI group according to abnormal area of ASL maps and DWI lesions.We observed and analyzed the ASL and DWI images of all patients.Results The paired samples test showed the results had statistical significance ( P <0.05).In 30 patients with cerebrovascular occlusion ,there were 29 cases in ASL>DWI group (29/30, 96.7%).There was 1 case in ASL≈DWI group (1/30, 3.3%).There was no 0 case in ASL<DWI group (0/30, 0%).In patients with cerebral infarction, there were 19 cases in ASL>DWI group (19/20, 95%).There was 1 case in ASL≈DWI group (1/20, 5%).There was no 0 case in ASL<DWI group (0/20, 0%).In patients with TIA, all for ASL>DWI group and DWI had no abnormal signals on the images.Conclusion ASL had important values for the diagnosis of cerebrovascular occlusion diease , combined with DWI scan, ASL can confirm the scope of the penumbra;ASL had values for early diagnosis of TIA and patients .