Assessment of therapy effect for chest malignity lesions with 18 F-FDG PET/CT imaging

CHEN Yi; PENG Yan-mei; PAN Xing-hua; DONG Li-hua; XU Xin-ming; LI Yi; YANG Hong-wen

Abstract：Objective This study was performed to evaluate the ability of 18 F-FDG PET/CT to assess therapy effect for chest lesion.Methods Ninety-nine cases with chest cancer were performed using 18 F-FDG PET/CT.Those imagings were compared between 18 F-FDG PET and CT on the same instrument .Results There were Eighty-seven cases in positive and eleven cases in negative in this study.Forty-four cases (34 in positive and 10 in negative) were surgery and chemotherapy and radiotherapy treat-ment.Fifteen cases (14 in positive and 1 in negative) were treated using radio-chemotherapy methods.Thirty-nine patients were treated by argon-helium cryotherapy (positive 39 cases).There were different in residual mass among 3 groups on PET/CT (χ2=24.40, P <0.001).There were 130 and 132 lesions on PET and CT of the same instrument respectively .The diameters of le-sions were 2.2~9.4 cm(average 5.20 ±1.73 cm) on PET and 1.0~10.6 cm (average 4.48 ±2.19 cm) on CT.The mass ex-tension was not significant different ( t =0.079, P >0.05) between PET and CT.There was a positive relationship ( r =0.85, P <0.01).The target and no-target rate of mass (T/NT) were 1.3~26.07 (average 6.32 ±5.48).There were discrimination that 18 F-FDG PET showed the viability of retain malignity mass and the anatomy change on CT .Conclusion There was an impor-tant role for assessment of therapy effects with chest malignity lesions of patients using the 18 F-FDG PET/CT.