The advantages and disadvantages of 3.0T spectroscopic imaging in the preoperative grading and postoperative follow-up of glioma
ZHANG Yuqin
XU Haidong
DONG Haibo
ZHOU Jinlong
Abstract：Objective To analyze the advantages and disadvantages of 3.0 T MRS imaging in brain glioma for the grading be-fore operation and follow up after operation .Methods We performed 2D-MRS examination on 61 cases, which had been consid-re gliomas by clinic and MRI , to observe the metabolite composition and ratio .We judged the preoperative level of glioma pro-spectively, compared with the results after operation to conduct retrospective analysis and followed up , and compared with 3D-ASL.Results We found the parenchyma of tumor decreased NAA , increased Cho.In high grade glioma, Cho/NAA was 5.3 ± 2.2, Cho/Cr was 3.5 ±1.5, in the lower, Cho/NAA was 1.6 ±0.3, Cho/Cr was 1.8 ±0.5, the difference was statistically sig-nificant ( P <0.05).At a mean follow-up of 6 months after operation, we found 12 cases of recurrence, and 7 patients with radi-ation encephalopathy , among these 4 cases were found in local tumor recurrence .Conclusion Magnetic resonance spectroscopic imaging could accurately judge glioma grade in the preoperatively , monitor tumor recurrence after operation sensitive .Compared with 3D-ASL, MRS was better in the invasion of peritumoral edema of tumor cells and tumor recurrence after operation and postop -erative radiotherapy , but it was easily affected by magnetic field stability , scanning positioning effect .Correct choice of scanning range could improve the diagnostic rate .
Keywords：GliomaMagnetic resonance imagingSpectroscopic imagingThree-dimensional arterial spin labeling
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 194-197 )