Relationship between the estrogen receptor, progesterone receptor and CerbB-2 expression levels and breast imaging re-porting and data system in invasive breast cancer patients
LI Yalin
LI Bbo
Abstract：Objective To explore the relationship between the estrogen receptor , progesterone receptor and CerbB-2 expres-sion levels and breast imaging reporting and data system in invasive breast cancer patients .Methods 120 patients with invasive breast cancers selected from september 2014 to september 2010 underwent ultrasonic examination and BI-RADS classification. CerbB-2, PR and ER positive expression were detected by immunohistochemistry method .We analyzed relationship of BI-RADS grading and ER ,PR and CerbB-2 positive expression .Results Tumor margin spiculation in ER and PR positive expression rate was significantly higher than the edge without spiculation persons ( P <0.05);internal with calcification CerbB-2 expression pos-itive rate was significantly higher than that of non calcified persons ( P <0.05);flow stage 0~ⅠER, PR, CerbB-2 expression positive rate had significantly higher than that of II ~III stage ( P <0.05).ER, PR, CerbB-2 positive expression rate with no significant correlation between tumor size , rear echo with or without attenuation , UE score ( P >0.05).The positive expression of ER, PR, CerbB-2 in IDC patients with BI-RADS stage was significantly higher than those in negative expression ( P <0.05). Conclusion IDC patients ultrasonic sign can predict the level of ER , PR and CerbB-2, so as to provide a reference for the treat-ment and prognosis of IDC .
Keywords：Estrogen receptorProgesterone receptorProto oncogeneInvasive breast cancersBreast imaging report and da-ta system
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 64-67 )