The applying values of three-dimensional ultrasound for diagnosis of fetal malformations of the central nervous system

YANG Jianjun; JIANG Hongfang; GENG Shujun

Abstract：Objective To investigate the applying value of three-dimensional ultrasound for diagnosis of fetal malformations of the central nervous system .Methods From August 2011 to January 2015, 320 women, who were suffered from high-risk preg-nancy as confirmed by prenatal ultrasound in our hospital , were selected in this work, and then, all were subjected to the two-di-mensional color Doppler ultrasound examination and three-dimensional ultrasound surface analysis .Results Via the two-dimen-sional ultrasound examination , the abnormalities of the fetal central nervous system were found in 28 patients, the detection rate was 8.75%;the main imaging characteristics exhibited that cerebellar cistern were widened , gray matter was heterotopic or gray matter signal appeared under the ependymal , and the development of corpus callosum was .By the the three-dimensional ultra-sound, the abnormalities of fetal central nervous system were checked out in 30 patients, the detection rate was 9.38%, in which two-dimensional ultrasound detected more than one patient with of hydrocephalus and one patient with choroid cysts by using the three-dimensional aspect with the lateral ventricles section .The satiation of misdiagnosis by the three-dimensional color Doppler was not seen as confirmed by the normal delivery or abortion autopsy , and the diagnostic accuracy was 100.0%;as for the situa-tion by the two-dimensional ultrasound , two patients were misdiagnosed , the diagnostic accuracy was 93.3%.Thus, the diagnos-tic accuracy by three-dimensional ultrasound was higher than that by the two-dimensional ultrasound .However, the difference by both methods was not statistically significant ( P >0.05).Conclusion Ultrasonography has higher detection rate for the abnor-malities of fetal central nervous system .Three-dimensional multi-slice imaging ultrasound can make up the misdiagnosis by dimen-sional color Doppler ultrasound , which significantly improves prenatal diagnostic accuracy .