PC-MRI study on hemodynamics of normal aduet basil ar artery

SHEN Lilong; ZHANG Liyun; OU Zhangsong; LIU Yuanfang

Abstract：Objective To investigate normal basilar artery hemodynamics features and differences between age groups .Mteh-ods 41 healthy volunteers were divided into three groups according to ages .There were 15 cases in young group , 16 cases in middle-aged group , 10 cases in elderly group .We used TOF-MRA to localize vertically in the middle of basilar artery , and arew ROI along the basilar artery’s edge in the PCA/M image, which showed the largest area of basilar artery .All parameters, LikeΔV, MV, MF, peak systolic velocity ratio ( PSVR) and end diastolic velocity ratio ( EDVR) in a cardiac cycle R-R interval were stastically analyzed, using SPSS 17.0 software.Results The averageΔV in the young, middle-aged and elderly groups was sig-nificantly statistical differences by analysis of variance among the groups ( F =7.54, P <0.01);Compared the means between every two groups, there was no difference between the middle a-ged and young groups ( t =1.74, P >0.05), but a significant differences between the elderly group and the young , middle-aged group ( t young vs elderly =8.9, t middle-aged vs elderly =7.4;P <0.01).The average MV, MF were respectively no difference when compared the means ( F =2.01, P >0.05).The average EDVR, PSVR were significant differences when compared the means in the three groups ( FEDVR=12.1, P <0.01, FPSVR=10.3, P <00.1);when using LSD-t test comparing the means between every two groups , there was no difference be-tween the middle-aged and young groups ( tEDVR=1.21, tPSVR =1.03;P >0.05), but between the elderly and the young , middle-aged groups (EDVR:t young vs elderly=10.2, t middle-aged vs elderly=7.3;PSVR:t young vs elderly=6.7, t middle-aged vs elderly=5.4, P <0.01).Conclusion There was no different about MV, MF in basilar artery between different age groups, but ΔV, EDVR and PSVR were higher in elderly group than in young and middle -aged groups .