Multimodal imaging findings and differential diagnosis of ganglioglioma

LIU Xue-bing; CHEN Zi-qian; XU Shang-wen; Liu Le

Abstract：Objective To evaluate the multimodal imaging findings of intracranial ganglioglioma .Methods Medical ima‐ging findings in twenty‐four with intracranial gangliogliomas confirmed by pathology were analyzed retrospectively .Results All cases were solitary .21 cases were supratentorial area ,including the temporal lobe (9 cases) ,the frontal lobe (7 ca‐ses) ,the frontal‐temporal lobe (2 cases) ,the thalamus and the pa‐rietal lobe respectively (1 multipe‐lesion case) .3 cases were subtentorial area ,including brainstem ,fourth ventricle and me‐dulla oblongata .The cystic‐solid tumors were ob‐served in 21 patients ,the solid lesion was observed in 1 patient and the cystic mass was observed in 2 patients .Non‐rein‐forcement could be seen in cystic compoments .Non‐reinforcement or Mild‐to‐moderate reinforcement could be seen in solid compoments .The solid components showed a reduced Cho/Cr and NAA/Cr ratio and an increased Cho/NAA ratio in MRS .In 3 cases with CT and 4 cases with PET‐CT plain scan ,calcification was seen in 5 cases .4 case showed poor me‐tabolizers in PET‐CT .Conclusion Although the medical imaging appearances of gang‐lioglioma are diversity ,intracranial gangliogliomas still have certain character‐istic imaging features ,which is helpful for the diagnosis pre‐operatively with a variety of imaging techniques .