A clinical trial of 125 I seed implants by CT-guided treatment implantation combined with bronchogenic arterial for advanced central-type lung cancer
LIN Yong
CHEN Jianping
YU Ping
HU Xiaokun
Abstract：Objective To evaluate the clinical effect of percutaneous radioactive particles 125 I implantation by CT‐guided treatment bronchogenic arterial for advanced central‐type lung cancer .Methods In this wook ,there were 42 cases of lung cancer that proved by pathology examine .All the 25 advanced central‐type lung cancer lesion from 21 patients were treated by CT‐guided percutaneous radioactive pieces 125 I implantation .After a week chemothrapy implantation ,medicament was injected through the arteries which provided blood to the cancer .We determined the healing effect through compareing the changes of tumours after 6 months and 12 months .Results Among 25 lesions in 21 cases ,following up for six months ,6 cases were CR(14 .3% ) ,30 cases were PR(71 .4% ) ,4 cases were NC(9 .52% ) ,2 cases were PD (4 .76% ) ,OR was 85.7 .% ,the total clinical response rate was 95 .2% .Among the opreation that 125 I granule was planted ,a smallamount of pneumothorax was found in 8 cases ,a small amount of lung bleeding was found in 9 cases .In one week after the opera‐tion ,there was 6 cases of phlegm with blood .Conclusion Percutaneous radioactive particles 125 I implantation by CT‐guided treatment combined with chemothrapy for advanced lung cancer has positive clinical effects in advanced central‐type lung cancer with minimal damage .
Keywords：Lung cancer125 I seedBronchogenic arterialInfusion chemothrapy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1381-1383 )