Study of 3T 1 HMR spectroscopy of peritumoral area in intracranial neoplasm
WANG Guo-hua
SHI Yan-yan
SONG Xiu-feng
LIU Guang-zhen
FENG Lei
WANG Hong-yan
XU Zhi-peng
YANG Xuan
Abstract：Objective To evaluate the clinical value of MR spectroscopy of peritumoral area in intracranial neoplasm (the brain astrocytomas ,metastatic tumors of the brain) .Methods Sixty‐six cases with brain neoplasm were collected from the Affiliated Hospital of Qingdao University .All the patients ,who were confirmed by pathology ,underwent proton MR Spectroscopy before stereotactic biopsy ,or operation .Results The Cho/Cr ratio of peritumoral area in high‐grade astro‐cytoma was significantly higher than that in low grade astrocytoma and brain metastatic tumors ( P < 0 .05) ,and the Cho/NAA ratio was significantly higher than that of low‐grade astrocytic tumor and brain metastases ( P < 0 .05) .The NAA/Cr ratio of peritumoral area in peritumoral NAA/Cr ratio was significantly higher than that in high‐grade astrocytoma ( P< 0.05) .The peritumoral metabolite ratios between low grade astrocytoma and brain metastases were not statistically sig‐nificant difference .The value of MI showed no statistical significant different between the four tumors .Conclusion MR spectroscopy of peritumoral area has significant value in detecting and differentiating brain tumors (such as the low grade astrocytoma ,high‐grade astrocytoma and metastatic tumors of the brain etc .) .
Keywords：Proton magnetic resonance spectroscopyBrain tumorsPeritumoral areaMagnetic resonance imaging
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 958-961 )