Analysis of radiologic and pathological features of the central neurocytoma

LIANG Bo; XU Zhi-feng

Abstract：Objective To investigate the clinical ,radiologic and pathological features of the central neurocytoma (CNC) in order to improve diagnostic level .Methods 12 patients with CNC were confirmed by surgy and pathology and the clini‐cal ,radiologicand pathological features of them were retrospectively reviewed .Results 11 lesions located in the lateral ventricle septum pellucidum ,adjacent to Monro hole ,and one lesion located in the right cerebellum hemisphere ,with ir‐rugular shape and sharp edge .5 patients underwent CT plain scans ,4 cases presented with different degrees of calcifica‐tion ,and their density was inhomogeneity ,with higher density for solid component .The majority presented as hypoin‐tense and equal signal intensity on T1 WI and inhomogeneous hyperintense signal on T2 WI .8 cases showed cyst‐ solidary , with multiple cystic degeneration in the borders of the tumors .On T2 WI ,3 cases showed “spongy” sign and 4 cases showed a “soap bubble” appearance ,of these case ,surrounding the cystic part showed “sponge gourd” patternlike areas on the postcontrast MRI .The postcontrast MR revealed solid part of 8 lesions demonstrated moderate or obvious enhance‐ment ,the thick enhanced vessels were found in 5 patients .All tumours were composed of monotonous neoplastic cells , and riched in blood vessels .The immunohistochemistry revealed syn(+ ) and NSE(+ ) .Conclusion CNC has the charac‐teristic appearances on MRI ,pathology and clinical data .When compaired with the onset age and typical part ,it will be helpful to the diagnosis and differentiates the neurocytoma from other tumors residing in lateral ventricle .