Application of diffusion tensor imaging and MRI in pre-surgical planning of brain neoplasms with 3 .0T MRI

WU Chuan-hua; JU Fa-jun

Abstract：Objective To explore the 3 .0 T magnetic resonance diffusion tensor imaging (DTI) and fMRI between brain neoplasms and adjacent brain white matter fiber tracts anatomical relationship in the role of Pre‐surgical panning .Methods 36 cases of brain neoplasms patients were taken the preoperative routine MRI scan ,enhanced scan and DTI technology in‐spection .After the original data acquisition processing and image analysis ,all the members of the fractional anisotropy (FA) ,color‐coded tensor figure ,cerebral white matter fiber tracts ,the determination of tumor lesion area of apparent dif‐fusion coefficient (ADC) values ,and peritumoral edema area all the members of the opposite fractional anisotropy (FA ) were aquired ,respectively .The relationship of the tumor and adjacent cerebral white matter anatomic were analyzed .And the clinical symptoms of patients before and after surgery were evaluated .Results The ADC and FA value ,between dif‐ferent grade of Astrocytoma lesion area ,peripheral edema area and normal white matter were significant differences ( P<0 .05) .The changes which contained compression ,displacement ,infiltration ,and destroy ,were visible in the white mat‐ter fiber tracts .4 cases of grade Ⅰ ~ Ⅱ Astrocytoma compressed adjacent cerebral white matter fiber tracts ,8 cases of grade Ⅱ ~ Ⅲ Astrocytoma invaded the brain white matter ;10 cases of grade Ⅲ ~ Ⅳ Astrocytoma destroyed of adjacent cerebral white matter fiber tracts .DTI chart can clearly display the relationship of the changes between motor area pyrami‐dal tract morphological and the tumor .On this basis to guide the operation ,the effect was satisfactory .Conclusion DTI , which is currently the only noninvasive technology in vivo ,can show the three dimensional white matter fiber tracts sur‐rounding brain tumors clearly .DTI and fMRI shows not only shift or change of brain’s important function area in the pathological circumstances but also the relations among the tumors ,the cerebral important function area and the white matter .In this sense ,this method is of great significance .