Assessment of changes of atrial electromechanical conducton in patients with hypertrophic obstructive cardiomyopathy by per -cutaneous transluminal septal myocardial ablation using tissue doppler imaging
WANG Shu-zhen
XIONG Feng
ZHANG Li-juan
FENG Kun
LIU Chun-xia
Abstract：Objective To investigate the severities of the atrial electrophysiological abnormalities in patients with hyper ‐trophic obstructive cardiomyopathy (HOCM ) compared with healthy controls and to evaluate the effects of percutaneous transluminal septal myocardial ablation (PTSMA) on the atrial electrophysiological conduction parameters .Methods We selectd 25 HOCM patients before and 6 months after septal ablation procedures and 26 healthy controls ,all of whom re‐ceived conventional echocardiography and tissue Doppler imaging .The intervals from the initiation of the P wave on the e‐lectrocardiogram (ECG) to the onsets of TDI‐derived late diastolic velocity at the lateral mitral annulus (P‐LA) ,anterior mitral annulus (P‐IVS) and tricuspid annulus (P‐RA) were measured .The intratrial asynchrony was defined as the differ‐ence between P‐LA and P‐IVS(T1 ) ,while ,the interatrial asynchrony as the difference between P‐LA and P‐RA(T2 ) .Re‐sults Compared with healthy controls ,P‐LA ,P‐IVS ,P‐RA and T1 ,T2 were significantly prolonged in HOCM patients . Moreover ,at 6 months after PTSMA ,the P‐LA ,P‐IVS ,P‐RA and T1 ,T2 were significantly decreased in HOCM pa‐tients .Conclusion Left atrial electromechanical conduction time ,left intratrial and interatrial asynchrony were significant‐ly prolonged in HOCM patients .PTSMA can improve the prolonged conduction time and asynchrony for HOCM patients .
Keywords：Tissue Doppler imagingHypertrophic obstructive cardiomyopathyPercutaneous transluminal septal myo-cardial ablationAtrial electromechanical conductionatrial fibrillation
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 218-221 )