The application of multivoxel magnetic resonance spectroscopy in the hippocampal sclerosis
XU Chang
MENG Hong-xiu
CH EN Liang
JIANG Xing-yue
WANG Pei-yuan
LI Quan
WANG Ping
BIAN Jia
Abstract：Objective To evaluate the value of multivoxel magnetic resonance spectroscopy in diagnosing hippocampal sclerosis early .Methods 28 patients were performed routine MRI and multivoxel magnetic resonance spectroscopy at bi‐lateral hippocampal areas .We measured N‐acetylaspartate acid (NAA) ,choline‐containing compounds (Cho) and Creatine (Cr) signal intensity in bilateral hippocampal areas .The distribution of metabolites in bilateral hippocampal areas would be analyzed .Results ① The diagnosis by the routine MR images in four cases was unilateral hippocampal atrophy and it was a consensus ,but four cases were inconsistency in the orientation of the disease side ,twenty cases were consider no mor‐phological changes in the hippocampus ; ② NAA ,the ratios of NAA / Cho ,NAA/Cr ,and NAA / (Cr + Cho) were de‐creased on ipsilateral side .Conclusion MRS is sensitive to the diagnosis of neuron abnormality and coincident well with the pathological results .It can provide useful information for presurgical diagnosis of hippocampal sclerosis .
Keywords：Magnetic resonance imagingSpectroscopy imageSclerosis of hippocampusEpilepsy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 204-206,217 )