Methods for judging the residual focus of hepatocellular carcinoma after TACE and for measuring the postoperative effective-ness of radioactive particle 125 I implantation
LUN Jun-jie
SUN Jian-ye
HU Xiao-kun
YIN Hao-zhi
LI Zi-xiang
Abstract：Objective To explore the methods for judging the residual foucus of hepatocellular carcinoma after transcath‐eter arterial chemoemblization (TACE) as well as for measuring the postoperative effectiveness of radioactive particle 125 I implantation in treating the residual lesions .Methods A total of 37 foci were found in 28 patients treated with TACE for 1~5 times .The methods for determining residual lesions were the enhanced CT for 10 cases ,the enhanced MRI for 8 ca‐ses ,PET‐CT for 6 cases ,and hepatic arteriography for 4 cases ,respectively .Pre-operative plan was made according to Brachy Interstitial‐Therapy Planning System to determine the amount and location of radioactive particle implantation .The target zone should be exceeded 0 .5~1 .0 cm from the tumor zone ,in which the radioactive particle 125 I was implanted un‐der the guidance of CT for the therapy of residual lesions .Meanwhile ,the serum level of AFP was regularly tested and compared with imaging results .Results All of the the enhanced CT ,enhanced MRI ,PET‐CT ,and hepatic arteriography can determine the residual tumors .28 patients with 37 lesions were duly accepted the treatment in line with the plan and re‐examined with CT scan at 2 ,4 ,6 ,and 12 months ,respectively .The local tomor control rates were 100% (37/37) , 100% (37/37) ,90 .9% (36/37) ,81 .8% (34/37) .The serum AFP and imaging were highly consistent .Conclusion The preferred methods to determine the residual lesions after TACE were the enhanced CT and MRI ,125 I seed implantation for therapy of residual lesions was effective .The serum level of AFP was the effective method to judge the efficacy of residual lesions treated with 125 I seed implantation .
Keywords：Hepatocellular carcinoma125 I radioactive particlesResidual lesionsBrachytherapyLocal efficacy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2125-2128 )